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IM means Intramuscular route of drug administration, while IV means Intraveinal route of drug administration.

IV route, takes the drug directly into the bloodstream resulting in 100% bioavailability instantly.

Where as in IM route, drug is injected into muscle tissues, which holds the drug for a while and gradually releases into the bloodstream through the network bed of capillaries running across or surrounding the muscle tissue. In IM, the bioavailability may be slightly less than 100% of drug due to diffusion from muscle through tissue fluid and into the blood.

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Q: What is the difference between an injection that is given IM OR IV?
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