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There are many different codes. In the DSM-IV-TR, soon to be replaced by the DSM 5.0, there is a code for Polysubstance-Related Disorder, 304.80. This is for the use of substances from at least three different substance groups to the point where overall use indicates dependence on substances, even though the use of substances from any one group would not rise to the level of dependence. Opiates/opioids would be an example of group. Any substances that are opiates or opioids would be from this one group.
There are separate DSM-IV-TR codes for several substances or groups of substances, with different codes for dependence on the substance and for abuse of the substance. In general codes in the form 305.xx indicate abuse of a substance and the .xx part is a specifier; this identifies the specific substance that is being abused. 305.60 is cocaine abuse, while 305.00 is alcohol abuse.
For substance dependence, the three digit codes will differ. 304.00 indicates opioid/opiate dependence, while 304.10 is for dependence on sedatives, hypnotics or anxiolytics. There are many other codes.
The new version of the DSM is coming out soon, and details at this time are very hard to obtain. There are changes to the Substance Related Disorders section. Keep checking for the new information over the next few months.
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