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One must define power in this case. The .45 transfers more energy to the target, is bigger, and can cause more damage. Overall, the .45 is more powerful. The .38spl and the .45 travel at close to the same velocity (depending on the powder load, projectile and firearm), yet the .45 is a ton heavier (up to 100gr heavier), that's a lot of energy imparted to the target. So, I would say the .45.
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