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The earliest sign of ALS is most often weakness in the arms or legs, usually more pronounced on one side than the other at first.

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What is the earliest sign of ALS?

ALS or Lou Gehrig's disease is a progressive disease that destroys nerves and muscles. Only a neurologist could diagnose it properly. The first signs that Lou Gehrig had were a slight slowing of his reactions and reduced strength. Nearly everyone over 40 has those symptoms! The ALS Association says weakness, reduced coordination, clumsiness, pain in hands and feet are all signs of ALS but that there is no one main early symptom. All of those symptoms could be caused by many other things.


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