Oh, dude, THC stands for tetrahydrocannabinol, the psychoactive compound in cannabis that gets you high. Mac could be short for Macintosh, the computer brand, and dev hd3 sounds like some tech jargon that's probably way over my head. So, like, if you're talking about getting high on a Mac computer, I'm not sure that's a thing, but hey, who knows in this crazy world?
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THC is tetrahydrocannibinol the chemical found in cannabis type plants.
MAC n DEV are snoop's and wiz's nick names in the soundtrack album and cover "mac and devin go to high school".
HD3 is a HDTV Cable Television network Euro1080's channel airing musical culture.