When I was a kid, I'm 50 now, we used to feed it to our horses every few weeks. I was told by a wonderful old "horseman" that if you feed tobacco to your horse it would kill internal parasites. According to our vet back then it did indeed kill some of them.
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For some kinds of small brain damage in specific parts of the brain, one of the components of tobacco allows the brain to function normally through effective blood flow, whereas the brain damage causing restricted blood flow would cause major confusion and an inability to focus, along with intense memory loss.
Medicines are available which include the specific tobacco component but the processing to eliminate the nicotine makes the costs prohibitive, and will not be covered by Medicare.
So in older patents over 50, where the long term dangers of tobacco are not likely relevant, smoking is an acceptable risk considering the alternative of losing all mental function and complete disability.
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Chewing, snuff. If you're habituated to tobacco, the safest thing to do is to use products that just contain the nicotine without the cancer causing stuff -- lozenges, gum, e cigarettes, etc.
smoking and in the olden days they use to feed it to horses to kill internal parasites