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The definition and significance of the Vdarea or Vd beta are studied based on the physiological clearance or pharmacolinetic modeling theory. It was found that the Vdarea calculated by dividing the intravenous dose by the beta. AUC. (where beta is the terminal phase exponential rate constant and AUC is the total area under the systemic arterial or venous plasma concentration vs. time curve from time zero to time infinity) can only serve as a proportionality constant to relate the total amount of compound present in the body and its systemic arterial plasma concentration during the terminal phase. Its use with the systemic peripheral venous plasma concentration may result in a significant overestimation of the amount present in the body because of the existence of the potential arterial-venous plasma concentration difference. The above new definition of the V can also be applicable to compounds undergoing the pulmonary first-pass elimination.

Q: Significance of the apparent volume of distribution?

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The volume distribution is the theoretical volume into which (for example a drug) is distributed into the body. The apparent volume is the volume into which the drug is KNOWN to distribute in the body.

Kd = (Ve - Vo)/(Vt - Vo) Ve = elution volume Vo = void volume Vt = volume total

in the significance of ph determination is in the evalucation of Quality in silages

The significance is that it tells you the place the electrons are locted in the atom.

it tells us about the distribution of energy amongst particles

Related questions

The volume distribution is the theoretical volume into which (for example a drug) is distributed into the body. The apparent volume is the volume into which the drug is KNOWN to distribute in the body.

It is a value around which the distribution lies.

The significance of the mean of a probability distribution is that it is the most probably thing to happen. The mean is the average of a set of values. If it is the average of a probability distribution, it is the most probable part.

No. They are required by law to settle an estate with expediency. If the executor, or co-executor, is delaying the distribution for no apparent reason they should be reported to the court. They can be replaced.No. They are required by law to settle an estate with expediency. If the executor, or co-executor, is delaying the distribution for no apparent reason they should be reported to the court. They can be replaced.No. They are required by law to settle an estate with expediency. If the executor, or co-executor, is delaying the distribution for no apparent reason they should be reported to the court. They can be replaced.No. They are required by law to settle an estate with expediency. If the executor, or co-executor, is delaying the distribution for no apparent reason they should be reported to the court. They can be replaced.

No. It is not apparent what 0.2422 refers to.

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The distribution of stars as seen from Earth is essentially random, but in such a random distribution people saw apparent collections of stars that seemed to make images.

Apparent Weight =weight Of Water- Upward Thrust =(mg- Density Of Water Displaced*volume Of Liquid*gravity)

yes

An efficiency template is a chart that distribution data is entered into in order to track, assess, and improve on all variables related to distribution. A distribution manager would need this data in order to track the effectiveness of the distribution system he is responsible for.

Binomial distribution is the basis for the binomial test of statistical significance. It is frequently used to model the number of successes in a sequence of yes or no experiments.

the Chi Square distribution is a mathematical distribution that is used directly or indirectly in many tests of significance. The most common use of the chi square distribution is to test differences among proportions