Well the next time she's annoying to you, politely ask her to stop, if this carries on say something like "I said can you please stop, are you having difficulty working out what that means?" If she STILL carries on just tell a teacher, then she will most likely stop, if she doesn't then just laugh at everything she's saying (not laughing at her comments laughing at how pathetic she is) Then if she is driving you mad don't ever say shutup or anything like that, because most of the time, that will make things worse, that's what she wants you to do, so to really annoy her, completely BLANK her out, pretend she's not there and ignore everything she's saying, that will really annoy her because she wants you to retaliate, so eventually she will get bored of you and stop. (If you are a boy she probably has a crush on you and is trying to get your attention)
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when girls say you are annoying they are obviously annoyed with something you did. if they say that through texting, they are pretty much telling you that you have to talk more because all girls hate it when boys don't talk a lot or send one word answers.. if it's in person, then try to think if you were being obnoxious or what you might have been doing wrong that got her mad.
It's important to communicate openly and honestly with the girl about how her behavior is affecting you. Let her know how you feel in a calm and respectful manner. If the behavior continues and is disruptive, it may be necessary to set boundaries or seek help from a trusted adult or counselor.