From my experience, to do what you want you'd need to run your Mic into a DAW, process it with the Autotune plugin (or a mixer and a hardware Antares Autotune processor) route it back to your mic input or to your software. There's probably a plugin for your MSN messenger or online game to do this easier.
If you have a Mac, GarageBand.
Autotune is a vocal pitch correction plug-in made by Antares. FL Studio owners can add on NewTone, a vocal pitch corrector as an online purchase for FL Studio 9, or buy Autotune and run it as a VST plugin.
You should be able to get software versions for very cheap or even free online.
Download Ateres Autotune online, you can buy it or get a 30 free trial or get it illegally for free. You have to install it as a separate program and it only works with audacity BETA. You will see it in your effects menu when you are done.
Online UPS is a power supply that is not interrupted during the switch-over of the power. There is a short cut-off on the offline UPS which can have an effect on affected loads during transition.
What you may be referring to is a voice changing software. You would need to download the program and run it while playing.
No
Mass Effect and Mass Effect 2 are both single player. There are no multiplayer modes
Guitars can be tuned quickly and easily by using an online tool such as the Tune-O-Matic. Guitars can also be tuned by buying a guitar tuning machine that listens to the sound of the guitar and tells the user if it is in tune or not.
There is neither a co-op mode or online mode for Mass Effect 2
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Yes. This phenomenon is known as the online disinhibition effect. Essentially, being online lowers your inhibitions.