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Statistically, death directly from marijuana overdose is extremely rare. The CDC reports that between 1999 and 2007, there were 26 deaths with marijuana as an underlying cause, in the United States. This was out of a counted population of 2,615,523,905. When it comes to smoking, most statistics say it will take about 800 joints in a short period of time to actually overdose a person to the point of death. A person should be vomiting or passed out well before this point. When used long term, the smoke itself does contain chemicals that can eventually cause respiratory issues, such as COPD or cancer.

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