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The Medulla is at the base of the brain stem and is the part of the brain that controls your heartbeat and breathing, etc. Therefore, when driving, the Medulla is active in ways such as controlling your heartbeat in reaction to stimuli (ie: if someone cuts you off, if a deer were to run in front of you, if something got you mad and gave you road rage, etc). Your heart rate would increase along with your respiration.

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