small .22 or .25 caliber handgun
$25 or so. Low value handgun.
The short answer is no. The longer answer is, you may be able to get a .25 cartridge into a .22 caliber gun, but it will likely jam and be very difficult to get out, and if it fires, it will probably damage the gun and possible the shooter. The .25 has a larger diameter than the .22.
It depends on what you mean. If you mean the most ineffective caliber, it's probably the .25 ACP or the .22 short. Some .25 cartridges have less energy than some .22 shorts.
Impossible to answer without more information.
No. The .22 is smaller in diameter than the .25 and would be too small for the chamber of a .25. Generally speaking, you should never try to fire any cartridge in any handgun other than what it is designed to fire. While it may be possible to get a cartridge to fire from a different gun, it may cause damage to the gun or the shooter. Additionally, I forgot to mention that the .22 is a rimfire cartridge and the .25 is a center fire, the the firing mechanism is slightly different in the two guns.
Assuming you mean a bullet fired from a .22 caliber handgun, the answer is, yes, it can, but it depends on several variables.
Yes, colt makes a few different versions of the 22 caliber handgun such as the Woodsman, and Challenger.
.22 handgun
The exact value of a 1910 Colt 22 caliber mini handgun would actually be highly dependent on a number of factors. Most importantly, the condition of the handgun.
25-65 USD
S&W never made a 25 ACP handgun for retail sale.