Before actually sending in a manuscript, it is best to contact a suitable publisher to see if they might be interested. At that time you can find out what format they want etc. Some are very fussy and want the manuscript typed using double spaces etc. Some will accept electronic submissions. It is not easy to get a manuscript accepted, so good luck!
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To submit a manuscript for publication, you typically need to follow the submission guidelines provided by the journal or publisher. This usually involves preparing your manuscript according to the specific formatting requirements, including a cover letter, abstract, figures, and references. Once your manuscript is ready, you can submit it through the journal's online submission system or via email as per the guidelines.