How do painkillers dissolve?

Answer 1

The answer depends on the formulation. Some are meant to dissolve later in the digestive tract than others, and some are meant to be absorbed through skin or mucous membranes.

Answer 2

Painkillers dissolve in the stomach and intestinal fluids of the body. Once ingested, the outer coating of the pill breaks down, allowing the active ingredients to be released and absorbed into the bloodstream. From there, the painkillers can travel to the affected area and reduce pain signals.