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Direct selection occurs when the bacteria are cultured in conditions where only the mutant will grow. For example, if a mutant bacterium has gained resistance to a specific antibiotic, only the mutant will be able to grow on media containing that specific antibiotic. Indirect selection occurs when the bacteria are cultured in conditions where the growth of the mutant is different from the growth of the wild type.

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Q: Difference between direct and indirect selection of mutant bacteria?
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