Prosthetic groups can be as simple as a single metal ion bound into the enzyme's structure, or may be a more complicated organic molecule (which might also contain a metal ion). it is permanently bonded to enzyme.
Activator is only metal ion that is detachable.
source:chemguide.co.uk
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An activator is a molecule that binds to an enzyme and enhances its catalytic activity, while a prosthetic group is a non-protein molecule that is permanently attached to an enzyme and is required for its activity. Prosthetic groups usually participate in the catalytic reaction, while activators simply increase the enzyme's efficiency.
A coenzyme is a non-protein compound that binds to an enzyme to help it function properly, while a prosthetic group is a non-protein component that is permanently attached to an enzyme and is essential for its activity. In other words, coenzymes are temporary helpers, while prosthetic groups are permanent additions to the enzyme structure.
Nitrate reductase does not contain the prosthetic group heme. Instead, it typically contains molybdenum cofactor (Moco) and heme iron-sulfur center as prosthetic groups.
A prosthetic group is a non-protein compound that is permanently attached to a protein, essential for the protein's function. It may participate in the catalytic activity of the protein or aid in binding other molecules. Examples include heme in hemoglobin and biotin in enzymes.
In organic chemistry, the main difference between tert-butyl and sec-butyl groups is their branching structure. Tert-butyl group has three methyl groups attached to a central carbon atom, while sec-butyl group has a methyl group attached to a secondary carbon atom. This difference in branching affects the reactivity and stability of molecules containing these groups.
A prosthetic group of an enzyme can be either organic or inorganic. Organic prosthetic groups are typically large molecules, such as coenzymes, that are often derived from vitamins. In contrast, inorganic prosthetic groups are usually metal ions that are required for catalytic activity, such as iron in heme groups.