Single ascending dose study: a small group of subjects receive single dose of the investigated drug; the dosage is escalated for a new group of subjects only when certain safety criteria are met after a period of observation time
Multiple asceding dose study: a group of subject receive multiple dosing of the investigated drug and a number of PK/PD parameters are observed. Later the dosage is escalated for another new group of subjects for multiple dosing, until a predefined dose level.
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Harmonic minor scale has a raised 7th in both ascending and descending scales. Melodic minor has raised 6th and 7th in ascending scale. It is similar to natural minor in descending scale.
There are millions, billions, trillions, actually an infinite number of numbers between 2.15 and 2.17.Here are ten examples, arranged in ascending order:2.1512.1552.162.160000000000012.16000000000012.1612.1622.1652.1692.16999999999999
Of a set of data the mode is the most, the median is the middle value in ascending order and the mean is the sum of the values divided by the number of values.
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Alphabetical order, such as with a list of countries ... Afghanistan all the way down to Zimbabwe that is descending order. Clicking on ascending starts the list the other way up, so Zimbabwe is at top and Afghanistan is last. For example. Same with numbers e.g. 1 down to say 500 or 500 down to 1 And so on ...