answersLogoWhite

0

3'-5' is a characteristic feature of DNA-polymerase I. This activity is meant to repair any misparing mistakes that the enzyme may commit during the synthesis, in which the enzyme would reverse its direction by ONE NUCLEOTIDE and excised the mistakenly added nucleotide, the enzyme acts at the phosphodiester bond at the 5 prime.

Whereas the 5'-3' exonuclease activity is an also repair strategy exercised by the DNA polymerase I. However, in this case the polymerase would move in the forwards direction and excise the miss-matched nucleotides at any position regardless with one nucleotide far or so many. This mechanism of repair is well documented in case UV-mutation.

User Avatar

Wiki User

13y ago

What else can I help you with?

Related Questions

What is the difference between DNA polymerase III and DNA polymerase I?

pol 1 - exonuclease activity pol 2 - dna repair pol 3 - primary replication enzyme


What is 3'5' exonuclease activity?

3'5' exonuclease activity refers to an enzyme's ability to degrade DNA or RNA molecules by removing nucleotides one at a time from the 3' to the 5' end of the strand. This type of exonuclease activity is important in proofreading and repairing DNA replication errors.


Is exonuclease activity 3-5 or 5-3?

Exonuclease activity can occur in both 3' to 5' and 5' to 3' directions, depending on the specific enzyme involved. 3' to 5' exonucleases remove nucleotides from the end of the DNA or RNA strand at the 3' end, while 5' to 3' exonucleases remove nucleotides from the 5' end. These activities play crucial roles in DNA repair, replication, and degradation processes.


Polymerase 1 without 5' to 3' activity is called?

Polymerase 1 without 5' to 3' activity is called exonuclease. It is responsible for removing RNA primers during DNA replication.


What is exonuclease activity?

Exonuclease activity refers to the enzymatic function of removing nucleotide residues from the ends of a nucleic acid molecule, such as DNA or RNA. This activity is crucial for processes like DNA repair, replication, and degradation of RNA. Exonucleases can act on either the 5' or 3' ends of nucleic acids, and their specificity and directionality play vital roles in maintaining genetic integrity and regulating gene expression.


What is the difference between 7 and 3?

The difference between 7 and 3 is 4.


The difference between a number and 3?

the difference between a number and 3 is


What is the difference between -3 and 1?

The difference between -1 and 3 is 4.


What type of biological molecule is an exonuclease?

An exonuclease is an enzyme that hydrolyzes nucleotides from the end of a nucleic acid chain. It is a type of protein, which is a biological macromolecule responsible for catalyzing biochemical reactions in living organisms.


What is the difference between 5.8 and 3?

It is 5.8 minus 3 = 2.8


What is the difference between -3 and -3?

Zero. In general, the difference between any number and itself is zero.


What is the difference of -4 and -3?

-1