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Prescription pills should only be taken as directed. However, it is possible to rectally administer Lortab (hydrocodone) in order to achieve recreational effects. However, the drug is absorbed faster (if the pills have been crushed and mixed with water) and possibly more extensively than when taken orally, and thus this practice carries an enhanced risk of overdose. If the pills are inserted intact, they take longer to dissolve, and the risks are similar to oral use.

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Q: Can you plug Lortabs in your butt to get high?
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