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Red blood cells of different groups have different molecules on the surface of their cells these are called antigens. People with blood type A will reject B type blood as they have different antigens on the surface of their cells, these differences are detected by antibodies. Blood type O has none of these antigens and so isn't rejected/detected by the antibodies.

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Blood group O can be safely transfused to any blood type because it does not contain A or B antigens on the surface of red blood cells. This reduces the risk of an immune reaction in the recipient's body, making it the universal blood type for transfusions.

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Q: Why is it safe to transfuse blood group O to a patient?
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Why anti A of O group not reacting with antigen A of A blood group?

In the ABO blood group system, individuals with blood type O do not have the A or B antigens on their red blood cells. Therefore, there is nothing for the anti-A antibodies in the plasma of an O blood type individual to react with when encountering blood from an individual with blood type A. As a result, there is no agglutination or clumping reaction between anti-A antibodies and A antigen on red blood cells, making it safe to transfuse blood between these blood types.


Which blood group should be of a donor to a patient who is 'O' negative?

An 'O' negative patient can receive blood from any blood type. However, 'O' negative is considered the universal donor for red blood cells because it lacks A, B, and Rh antigens, making it safe for almost everyone to receive.


Is it safe to color your blood?

No, it is not safe to color your blood. Coloring your blood can interfere with its ability to carry oxygen, potentially causing health problems. It's best to avoid altering the color of your blood.


Why is blood group O not always a universal donor?

While blood group O is considered a universal donor for red blood cells, it may not be a universal donor for plasma. The presence of certain antibodies in blood group O individuals can cause adverse reactions when given to recipients with specific blood types. Compatibility testing is still necessary to ensure safe blood transfusions.


What is blood letting procedure?

Bloodletting is a medical practice of withdrawing blood from a patient to treat various conditions, which was popular in ancient times. It was believed to balance the body's humors and promote health, but it is now considered outdated and potentially harmful. Modern medicine has more effective and safe treatments for most conditions that historically were treated with bloodletting.