DNA has a net negative charge (which is due to the phosphate backbone) and is Acidic nature and histones which have a pI of ~10 are basic and overall have a positive charge (histones are right in argenines and lysines). Opposites attract, + and - are attracted. :) hope this helps
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DNA wraps around histone proteins to form a structure called a nucleosome. This packaging allows for compaction of DNA, making it more efficient for storage in the cell. Additionally, the interaction between DNA and histones plays a role in gene regulation by influencing accessibility of DNA for transcription factors.
The section of DNA with eight associated histone proteins is called a nucleosome. Nucleosomes are the basic unit of DNA packaging in eukaryotic cells, where DNA is wrapped around a core of histone proteins to form a chromatin structure.
The enzyme responsible for unwinding DNA from around histone proteins is called DNA helicase. It catalyzes the separation of the two strands of the DNA double helix, allowing access for other enzymes and proteins to interact with the DNA.
The DNA is wrapped around histone proteins to form nucleosomes, which then coil up to form chromatin. This complex helps package the long DNA molecule into a more compact structure, which allows it to fit inside the cell nucleus.
its quite intresting to kno dat in a single cell the length of DNA integrated is about 2metres or more. so to accomodate dat much length of smething it needs to b wrapped. it can can b thought of packing a heap of clothes in a small suitcase. So it has to be compacted to a level of packing called nucleosomes.
Histone proteins