Mast Cells are well known for their harmful role in IgE-mediated
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Mast cells are important in the immune response as they release histamine and other inflammatory mediators in response to allergens and pathogens. This triggers inflammation and helps recruit other immune cells to the site of infection. Overactive mast cell activity can lead to allergic reactions and Asthma.
A decrease in the population of T lymphocytes (T cells) would impair all aspects of an immune response. T cells play a critical role in coordinating and regulating the immune response, including activating other immune cells such as B cells and macrophages, and directly killing infected cells.
Regulatory T cells (Tregs) are a type of immune cell that suppress the immune response to prevent overactivity. They play a crucial role in maintaining immune tolerance and preventing autoimmunity by controlling and regulating the activity of other immune cells.
Langerhans cells are epidermal cells that play a key role in the immune response by capturing and presenting antigens to immune cells. They are part of the skin's immune system and help in defending against pathogens.
These granulocytes are mast cells, not the typically recognized granulocytes like neutrophils, eosinophils, and basophils. Mast cells are tissue-resident immune cells that play a key role in allergic reactions and inflammation. They release histamine and heparin upon activation, contributing to immune responses and the regulation of vascular permeability.
B cells play a role in producing antibodies, while T helper cells (Th cells) help activate and coordinate the immune response. Cytotoxic T cells (Tc cells) are responsible for directly killing infected cells. Both Th cells and Tc cells are types of T cells, with Th cells regulating the immune response and Tc cells directly attacking infected cells.