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B-12 refers to a group of cobalt-containing vitamer compounds known as cobalamins: these include cyanocobalamin (an artifact formed as a result of the use of cyanide in the purification procedures), hydroxocobalamin (another medicinal form), and finally, the two naturally occurring cofactor forms of B-12: 5-deoxyadenosylcobalamin (adenosylcobalamin-AdoB-12), the cofactor of Methylmalonyl Coenzyme A mutase (MUT), and methylcobalamin (MeB-12), the cofactor of 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR).

The term B-12 may be properly used to refer to cyanocobalamin, the principal B-12 form used for foods and in nutritional supplements.[1]

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Explain the relation between vitamin b12 and pernicious anemia?

first of all its called vitamin b12 deficiency anemia. Pernicious anemia and vitamin B12 deficiency anemia are the same thing. Pernicious anemia is caused by a lack of vitamin B12. You're not able to absorb the vitamin B12 due to the absence of intrinsinc factor.


A protein secreted by the stomach that is necessary for the absorption of vitamin B12?

The protein secreted by the stomach that is necessary for the absorption of vitamin B12 is called intrinsic factor. Intrinsic factor binds to vitamin B12 in the small intestine, allowing for its absorption into the bloodstream. Without intrinsic factor, vitamin B12 cannot be effectively absorbed and can lead to a deficiency.


Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?

Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.


Scientific name of vitamin E?

Eight forms of vitamins E are known; see the link below for details.


Can a Vitamin B12 deficiency be connected to something serious like leukemia?

A Vitamin B12 deficiency is not directly linked to leukemia. Leukemia is a type of cancer that affects blood cells and is caused by genetic mutations, while vitamin B12 deficiency usually results from dietary factors or malabsorption issues. However, some symptoms of Vitamin B12 deficiency, such as anemia, fatigue, and weakness, may overlap with symptoms of leukemia, so it is important to consult a healthcare professional for proper evaluation and diagnosis.