Although there may be a brief euphoria, the risks include nausea, dizziness, balance problems, confusion/delirium, and even psychotic symptoms for some. Inhalant intoxication, especially on a repeated basis, causes brain cell death, and there are numerous cases of individuals with persistent concentration problems, headaches (and many more symptoms).
Probably most people (who have used permanent markers) have noticed some brief effects, but it is the repeated use that becomes a problem.
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Sniffing sharpies can cause dizziness, nausea, headaches, and in some cases, even unconsciousness. This is due to the chemicals, specifically solvents, found in permanent markers that can be harmful when inhaled in large amounts. It is important to avoid sniffing any kind of marker or inhaling their fumes.
Sniffing solvents can refer to inhaling fumes from household products like glue, paint thinner, or gasoline to get high. This practice can be very dangerous, leading to serious health issues like brain damage, respiratory problems, and even death. It is illegal to misuse solvents in this way.
Accidents from sniffing solvents can include dizziness, nausea, vomiting, headaches, and in severe cases, loss of consciousness, heart complications, or death. Long-term use can lead to damage to the brain, liver, kidneys, and other organs.
If anything toxic comes out, the toxins would have affected the owner of the anus, so no.
If you find someone unconscious after sniffing solvents, the first step is to call for emergency medical help. While waiting for help to arrive, move the person to fresh air and monitor their breathing. Do not try to make them "snap out of it" or induce vomiting.
Endothermic reaction.