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GCMS involves running the sample through a mass spectrometer following the data received from chromatography. MS fragments the analytes to show patterns specific to the analyte (and the ionization technique and sector powers) therefore allowing the analyte to be identified. GC is used to separate all volatile substituents of a sample so they can be identified one by one.

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What does LC-MS mean in toxicology?

LC-MS is the abbreviation for Liquid Chromatography - Mass Spectrometry. It is a method for doing analysis.


What is difference between high pressure liquid chromatography and high performance lequid chromatography?

High pressure liquid chromatography (HPLC) and high performance liquid chromatography (HPLC) are often used interchangeably. HPLC refers to modern liquid chromatography systems with high resolution and efficiency, while high pressure liquid chromatography specifically highlights the use of higher pressures in the system to improve separation and speed. Both terms generally refer to the same chromatographic technique.


What general techniques of laboratory investigations of compounds do you know?

Some general techniques of laboratory investigations of compounds include spectroscopy (such as UV-Vis, IR, and NMR), chromatography (such as gas chromatography and liquid chromatography), mass spectrometry, and X-ray crystallography. These techniques are commonly used to analyze the structure, composition, and properties of compounds.


How do you obtain chromatogram?

A chromatogram is obtained by running a sample through a chromatography technique such as gas chromatography (GC) or liquid chromatography (LC). The components of the sample separate based on their unique properties as they move through the stationary phase in the column. Detection methods such as mass spectrometry or ultraviolet-visible spectroscopy are then used to generate a chromatogram showing the peaks corresponding to each component.


What difference between dad and uv detector in hplc?

Liquid chromatography (LC) encompasses all chromatographic techniques using liquid mobile phase, including planar chromatography (paper chromatography and thin-layer chromatography) and column chromatography (classical column chromatography, and high-performance liquid chromatography on packed and capillary columns). The term liquid chromatography is nowadays often used as a sinonim for high performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC).

Related Questions

What has the author O David Sparkman written?

O. David Sparkman has written: 'Gas chromatography and mass spectrometry' -- subject(s): Gas chromatography, Mass spectrometry


What has the author W M A Niessen written?

W. M. A. Niessen has written: 'Liquid chromatography--mass spectrometry' -- subject(s): Liquid chromatography, Mass spectrometry


What is the process of 'difference spectrometry'?

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What has the author S-T F Lai written?

S.-T. F. Lai has written: 'Gas chromatography/mass spectrometry operation' -- subject(s): Gas chromatography, Mass spectrometry


What has the author William H McFadden written?

William H. McFadden has written: 'Techniques of combined gas chromatography/mass spectrometry' -- subject(s): Gas chromatography, Mass spectrometry, Organic Chemistry


What is L.C.M?

Liquid chromatography - mass spectrometry. LC is the separation, MS is the detection


What type of laboratory testwould NOT be conducted if you suspect a patient has contracted plague?

When the plague happened there were no labs or testing. They didn't know or understand the transmission of disease or anything about virus and disease.


How can one identify compounds in gas chromatography?

Compounds in gas chromatography can be identified by comparing their retention times to known standards or using mass spectrometry to analyze their molecular structure.


What has the author William L Budde written?

William B. Gudykunst has written: 'Theorizing About Intercultural Communication' 'Communication Yearbook 25 (Communication Yearbook)' 'Building Bridges' 'Communicating with strangers' -- subject(s): Intercultural communication, Intergroup relations 'Communication Yearbook 26 (Communication Yearbook)'


What does LC-MS mean in toxicology?

LC-MS is the abbreviation for Liquid Chromatography - Mass Spectrometry. It is a method for doing analysis.


What is difference between high pressure liquid chromatography and high performance lequid chromatography?

High pressure liquid chromatography (HPLC) and high performance liquid chromatography (HPLC) are often used interchangeably. HPLC refers to modern liquid chromatography systems with high resolution and efficiency, while high pressure liquid chromatography specifically highlights the use of higher pressures in the system to improve separation and speed. Both terms generally refer to the same chromatographic technique.


What is the difference between anion and cation exchange chromatography?

Anion exchange chromatography separates molecules based on their negative charge, while cation exchange chromatography separates molecules based on their positive charge.