The addition of a phosphate group to an organic molecule. Phosphorylation is important for many processes in living cells. ATP is formed during cell respiration from ADP by phosphorylation, as in the mitochondria of eukaryotic cells (oxidative phosphorylation) and the chloroplasts of plant cells (photosynthetic phosphorylation). Phosphorylation also regulates the activity of proteins, such as enzymes, which are often activated by the addition of a phosphate group and deactivated by its removal (called dephosphorylation).
simplified for dummies like me : The addition of a phosphate group to a molecule.
edited and simplified by Holy122 :P
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Phosphorylation is a biochemical process that involves the addition of a phosphate group to a molecule, typically a protein, to regulate its function, activity, or localization within the cell. This modification alters the structure and function of the target molecule, often serving as a key mechanism for cellular signaling and control of various cellular processes.
Cytoplasmic or soluble enzymes can carry out phosphorylation that does not require a membrane. This type of phosphorylation occurs in the cytoplasm or within organelles like the mitochondria and does not involve a membrane-bound protein complex.
Its a process which generates ATP using substrate level phosphorylation. This process is anaerobic (does not need oxygen) and generates two net ATP per molecule of glucose
Phosphorylation typically does not denature a protein. Phosphorylation is a reversible modification where a phosphate group is added to a protein, often regulating its function, structure, or localization within the cell. However, extreme or incorrect phosphorylation can lead to protein misfolding and dysfunction.
Two methods of phosphorylation are: Enzyme-catalyzed phosphorylation, where enzymes like kinases transfer phosphate groups from ATP to specific proteins. Photo-phosphorylation, which occurs during photosynthesis where light energy is used to convert ADP and inorganic phosphate into ATP.
it adds a phosphate group Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule.