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A physiological saline is a solution of salts and sugars intended to act as a medium for growing or maintaining live tissue. The solution mimics the salt concentrations of the tissues' natural environment, while providing some buffering to maintain the pH of the solution. Since different tissues from different species are subject to varying internal environments, a large number of physiological salines have been developed over the last century. For example, the original Ringer's solution was developed to mimic amphibian blood, Hank's solution was intended for human tissue, Cortland's saline was designed for the tissue of freshwater fishes, and phosphate-buffered saline is commonly used as a divalent-free saline that is isotonic with human blood. While the composition of every solution is unique, physiological salines developed for vertebrates (such as those mentioned above) have much in common. Such salines are predominately sodium chloride with a concentration of about 0.9% (or 9.0g/L). In lesser concentrations, they often include: sodium monobasic phosphate, sodium dibasic phosphate, sodium bicarbonate, potassium chloride, calcium chloride, magnessium chloride, magnessium sulfate, and glucose.
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RafaPhysiological saline, also known as saline solution, is typically composed of 0.9% sodium chloride (NaCl) dissolved in water. This concentration closely matches the salt concentration found in human blood and is commonly used in medical settings for hydration, irrigation, and certain medical procedures.
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What is the difference between normal saline and physiological saline?
normal saline is 0.85%w/v NaCl whlist physiological saline is 0.90% w/v NaCl.
What effect did administration of saline injections have on the control rat?
Administration of saline injections had no pharmacological effect on the control rat since saline does not contain any active drug. The control rat would not experience any physiological changes or behavioral effects from receiving saline injections.
What buffer is better water saline or TBS?
The choice between water, saline, or TBS buffer depends on the specific application and requirements of the experiment. Water is used for dissolving samples, while saline solution is preferred for cell culture and physiological studies. Tris-buffered saline (TBS) is commonly used for Western blotting and immunohistochemistry due to its compatibility with antibody binding.
Can saline solution such as for contact lenses work as a fluid to use in syringes to do practice injections?
Saline solution for contact lenses is not typically recommended for use in syringes for practice injections. It may not have the same viscosity, density, and composition as medical saline solution used for injections, which could affect the accuracy and safety of the practice. It is best to use appropriate medical-grade saline solution for practice injections.
How do you make a physiological salt solution?
To make a physiological salt solution, mix 0.9% sodium chloride (commonly known as saline solution) with sterile water. This solution closely matches the salt concentration in the human body and is commonly used for medical purposes like intravenous hydration or wound cleaning.
