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EzraSalicylic acid is more polar than aspirin because it has a higher solubility in water due to the presence of a hydroxyl group that enhances its polarity. Aspirin, on the other hand, has an ester functional group, which reduces its overall polarity compared to salicylic acid.
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Why salicylate is more soluble than salicylic acid?
Salicylate is more soluble than salicylic acid because salicylate is an ionized form of salicylic acid that can interact with water molecules through polar interactions, increasing its solubility in water. Salicylic acid, in its non-ionized form, has fewer interactions with water molecules, decreasing its solubility.
Is aspirin the strongest acid?
No, aspirin is not an acid in terms of acidity strength. Aspirin is a weak acid called acetylsalicylic acid. Strong acids like hydrochloric acid have a much lower pH and can fully dissociate in solution.
How does aspirin dissolve in carbohydrate solution?
Aspirin is a weak acid that can dissolve in water due to its polar structure and hydrogen bonding. When aspirin is added to a carbohydrate solution, it can form hydrogen bonds with the hydroxyl groups of the carbohydrate molecules, helping it dissolve more readily in the solution.
Why does aspirin dissolve in water?
Aspirin is a polar molecule due to the presence of functional groups like carboxyl and phenyl groups. Water is also a polar molecule. The interactions between the polar molecules of aspirin and water lead to the dissolution of aspirin in water through hydrogen bonding and other intermolecular forces.
Why acylation occur at phenol rather than carboxylic acid in salicylic acid?
Acylation occurs at the phenol group in salicylic acid due to the higher reactivity of the phenol hydroxyl group compared to the carboxylic acid group. The phenol group is more nucleophilic and readily reacts with acetyl chloride to form acetylsalicylic acid (aspirin). Additionally, the carboxylic acid group can interfere with the reaction due to its ability to form hydrogen bonds, making it less reactive towards acylation.
