The hemoglobin A1c, or glycohemoglobin, is a measure of how much sugar is attached to the hemoglobin protein in the blood. Sine hemoglobin is removed from the blood along with the red cell in which it is resides measuring the a1c can give an estimate of ow high the sugar has been averaging over the life of the red cell, which is usually about 120 days (4 months).
The most recent time frame has a larger effect on it than more distant times so it is often, somewhat inaccurately, said to give a 3 month average. It can be affected by anemia, blood loss, blood transfusions and abnormal hemoglobins.
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Hemoglobin A1c (HbA1c) is a common blood test used to measure average blood sugar levels over the past 2-3 months. It is primarily used to monitor long-term Diabetes control and the risk of complications associated with high blood sugar levels. A higher HbA1c level indicates poorer diabetes control.
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You have Iron atoms in hemoglobin. This atom is the binding site for oxygen in case of hemoglobin.
Iron is the mineral that enables red blood cells to carry oxygen. It is a key component of hemoglobin, the protein in red blood cells that binds to oxygen and transports it throughout the body.
Hem from hemoglobin is recycled for production of hemoglobin.
The difference in electrophoretic pattern between normal hemoglobin A and hemoglobin S is due to a single amino acid substitution. In hemoglobin S, a glutamic acid is replaced by a valine at position 6 of the beta-globin chain. This change causes hemoglobin S to have a different charge, leading to its characteristic migration pattern on electrophoresis.