answersLogoWhite

0


Best Answer

Terminal plasma half-life is the time required to divide the plasma concentration by two after reaching pseudo-equilibrium, and not the time required to eliminate half the administered dose. When the process of absorption is not a limiting factor, half-life is a hybrid parameter controlled by plasma clearance and extent of distribution. In contrast, when the process of absorption is a limiting factor, the terminal half-life reflects rate and extent of absorption and not the elimination process (flip-flop pharmacokinetics). The terminal half-life is especially relevant to multiple dosing regimens, because it controls the degree of drug accumulation, concentration fluctuations and the time taken to reach equilibrium.

User Avatar

Wiki User

16y ago
This answer is:
User Avatar
More answers
User Avatar

AnswerBot

5mo ago

Terminal half-life is the time it takes for the concentration of a drug in the body to decrease by half during the elimination phase, after reaching steady state. It is used to estimate how long a drug will stay in the body once the dosing is stopped. Terminal half-life is influenced by factors such as drug metabolism and elimination rate.

This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: What is Terminal half life?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Related questions

What is the half life morphine sulfate er?

It's terminal elimination half-life after intravenous administration is normally 2 to 4 hours. In some studies involving longer periods of plasma sampling, a longer terminal half-life of about 15 hours was reported.


Does Half life opposing force require Half life?

No. Half Life: Opposing Force does not require neither Half Life nor Half Life: Blue Shift.


What is terminal leukemia?

a cancer that will eventually be life-ending


Can you get a life insurance policy if you have terminal cancer?

yez


Is half life opposing force on Playstation 2?

No, only Half-Life and Half-Life: Decay.


Is there more blood in half life or Half Life Source?

Most likely Half Life Source


The time it takes for half of the radioactive element to decay is the element's what?

The time it takes for half the atoms in a sample of a radioactive element to decay is called the half life.


What is the half life of antibiotics?

Antibiotics do not have a half life.


What is the best way to say I missed half of my life or I've missed half of my life?

You say 'I've missed Half my life' which is short for : "I have missed half my life'


What is the term given to the time it take for one half of a sample of radioactive nuclei to decay?

The term is called half-life. It is the time it takes for half of the radioactive nuclei in a sample to decay.


How do you import half life 1 weapons into half life 2?

Buy Half Life: Source Or Buy Garrysmod a Half-Life 2 Modification and get the addon "Half-Life Rennaisance" Link to Half Life Rennaisance: http://www.garrysmod.org/downloads/?a=view&id=57033 Enjoy!


Can half-life source be used for half-life mods?

No. Half-Life: Source runs on the Source engine. The original Half-Life doesn't. You cannot use mods made for the original Half-Life on Half-Life: Source because they run on different engines and it won't work.