RNA polymerase can transcribe mRNA
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When the cell is not in the presence of tryptophan, it activates a regulatory protein called the trp repressor. This repressor binds to the DNA in the promoter region of the operon controlling tryptophan synthesis, preventing RNA polymerase from transcribing the genes. As a result, the production of enzymes involved in tryptophan synthesis is inhibited.
The expression of the tryptophan operon is controlled by a repressor protein that binds to the operator region in the presence of tryptophan. When tryptophan levels are high, the repressor is active and prevents transcription of the operon. When tryptophan levels are low, the repressor is inactive, allowing transcription to occur.
If Tryptophan is low in the diet, the repressor changes shape and allows the RNA polymerase to attach and copy the DNA so that Tryptophan can be produced by the cell.
Tryptophan
Vitamin B3, also known as niacin, can be synthesized in the body from the essential amino acid tryptophan. Tryptophan is converted into niacin through several metabolic pathways.
Tryptophan.