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When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.

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At the neuromuscular junction, the muscle contraction initiation event is?

 binding of acetylcholine to membrane receptors on the sarcolemma


What part of the muscle cell membrane contain acetylcholine receptors?

Acetylcholine receptors are located on the motor end plate of the muscle cell membrane. This specialized region is where the nerve cell communicates with the muscle cell, allowing for the initiation of muscle contraction in response to acetylcholine binding to its receptors.


What is the chemical transmitter released at the neuromuscular junction?

Acetylcholine is the primary chemical transmitter released at the neuromuscular junction. It binds to acetylcholine receptors on the muscle cell membrane, leading to muscle contraction.


The chemical that transmits the signal across the neuromuscular junction is called?

Acetylcholine is the chemical that transmits signals across the neuromuscular junction. It binds to receptors on the muscle cell membrane, leading to muscle contraction.


What is the neurotransmitter used at the neuro muscular junction is?

The neurotransmitter used at the neuromuscular junction is acetylcholine. It is released from the motor neuron terminals and binds to receptors on the muscle cell membrane, leading to muscle contraction.


What is released to muscle cell receptors to trigger muscle contractions?

Acetylcholine


What is ACh receptors?

Acetylcholine (ACh) receptors are protein molecules on the surface of cells that bind to acetylcholine, a neurotransmitter in the nervous system. These receptors are involved in transmitting signals between nerve cells and muscle cells, and are crucial for various physiological processes such as muscle contraction, heart rate regulation, and memory functions. There are different types of ACh receptors, including nicotinic and muscarinic receptors, each having distinct roles and locations in the body.


What is the transmission of the stimulus at the neuromuscular junctions involves?

The transmission of the stimulus at the neuromuscular junction involves the release of acetylcholine from the motor neuron, binding to acetylcholine receptors on the muscle cell membrane, causing depolarization of the muscle cell, and ultimately leading to muscle contraction.


Where does the acetylcholine released for muscle contraction bind?

Sarcolema receptors


Chemical released to stimulate muscle contraction?

Acetylcholine is the primary neurotransmitter released by motor neurons at the neuromuscular junction to stimulate muscle contraction. It binds to receptors on the muscle cell membrane, initiating a series of events that ultimately lead to muscle contraction.


What happens when acetylcholine receptors are blocked?

Blocking acetylcholine receptors can lead to a decrease in cholinergic transmission in the body. This can result in muscle weakness, altered heart rate, and impairments in cognitive function. Blocking these receptors is a mechanism of action for certain medications, such as neuromuscular blocking agents used during surgery.


How does curare cause muscle paralysis?

Curare is a competitive inhibitor of acetylcholine. It fights with acetycholine for postsynaptic receptors.