No, Izzie does flatline but she doesn't die. She comes back for one episode of season 6, but then is fired from Seatlly Grace hopital. Katherine Hiegl leaves the show because she wanted to be close with her family.
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Izzie didn't die on Grey's Anatomy. The character did have cancer but survived it. Izzie just left Seattle, she didn't die.
Shondra Rimes, the show's creator, was going to kill the character off, but decided against it. She also wanted to bring Katherine Heigl back as a guest star to give the character's story closure, but so far they haven't been able to get her to come back.
Izzy does not die on Grey's Anatomy. She walks out on Alex after her cancer is more under control and she is never heard from again.
Izzie had a small time in death after coding due to her struggle with cancer. She was brought back to life, and then she left the series shortly after.
Yes, Mark Sloan dies in Grey's Anatomy after sustaining injuries from a plane crash. He is taken off life support after being declared brain dead.
I'm here to provide information up until September 2021, and as of that time, Derek Shepherd's character died in Season 11 of Grey's Anatomy.
Izzie Stevens, played by Katherine Heigl, dies in the season 6 finale of Grey's Anatomy, which is titled "Death and All His Friends."
Lexie Grey dies in the season 8 finale of Grey's Anatomy titled "Flight." She succumbs to her injuries after a plane crash that leaves her trapped in the wilderness with her fellow colleagues.
In the plane crash in Grey's Anatomy, Lexie Grey and Mark Sloan die.