The Kell family of antigens found on red blood cells have been associated with hemolytic transfusion reactions and with hemolytic disease. Individuals lacking a specific Kell antigen and having a blood transfusion may experience destruction of the new cells by hemolysis. To avoid this, they must be transfused with blood from donors who are also K0. Autoimmune hemolytic anemia may also occur when the body produces an antibody against a K blood group antigen on its own red blood cells, leading to destruction of the red blood cells with resulting anemia.
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Kell positive blood refers to the presence of the Kell antigen on the surface of red blood cells. This antigen is part of the Kell blood group system and can be important in blood transfusions and pregnancies. A person who is Kell positive can safely receive blood from Kell negative donors, but a Kell negative person should only receive blood from donors who are also Kell negative to prevent potential adverse reactions.
If your blood group is O RH positive Kell negative, it means you have blood type O, are Rh-positive, and do not have the Kell antigen on your red blood cells. This information is important for blood transfusions to ensure compatibility with donor blood.
Having O positive blood with an Rh(Kell) negative blood type is relatively rare. The O positive blood type is the most common blood type, but the combination of O positive with Kell negative is less common. It is important to discuss any concerns with your healthcare provider regarding blood compatibility for any future medical needs.
Apparently, the Kell blood group system is separate from the ABO and Rh blood groups. The Kell blood group can also trigger immune reactions. According to nih.gov, "Antibodies that target Kell antigens can cause transfusion reactions and hemolytic disease of the newborn (HDN). In the case of HDN, ABO and Rh incompatibility are more common causes. However, disease caused by maternal anti-ABO tends to be mild, and disease caused by maternal anti-Rh can largely be prevented. The infrequent cases of HDN caused by Kell immunization tend to result in severe fetal anemia because maternal anti-Kell target fetal red blood cell (RBC) precursors, suppressing the fetal production of RBCs."
Yes, a parent with O positive blood and a parent with A positive blood can have children together. The child could inherit either parent's blood type, resulting in the child having either O positive or A positive blood type.
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