The nucleolus within the nucleus is where ribosomes are manufactured.
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# Nucleolus.
ribosomes
ribosome
nucleolus
Erythromycin does not affect mitochondrial 70S ribosomes because mitochondrial ribosomes are structurally different from bacterial ribosomes. Erythromycin targets the specific structure of bacterial ribosomes without affecting the similar but different structure of mitochondrial ribosomes found in eukaryotic cells. This difference in ribosome structure allows erythromycin to selectively target bacterial ribosomes while sparing eukaryotic mitochondrial ribosomes.