Microglia are small phagocytic cells that are especially obvious in damaged tissue in the central nervous system (CNS). They are the resident immune cells of the CNS and act as the primary form of active immune defense in the brain.
MHC (Major Histocompatibility Complex) proteins act as a fingerprint of the cell by presenting peptide fragments on the cell surface for immune system recognition. This enables the immune system to distinguish between self and non-self cells, helping to prevent an immune response against the body's own cells.
Microglial cells are the macrophages of the central nervous system (CNS). They act as the primary immune cells in the brain and spinal cord, performing functions like phagocytosis, antigen presentation, and cytokine release to regulate the immune response in the CNS.
The key secretions that control the process of inflammation are cytokines, chemokines, and prostaglandins. These molecules act as signaling agents to recruit immune cells to the site of inflammation, amplify the immune response, and promote the resolution of inflammation.
Dendritic cells are a type of immune cell that play a key role in activating the immune system by capturing, processing, and presenting antigens to other immune cells. They act as messengers between the innate and adaptive immune systems, helping to initiate an immune response against invaders such as pathogens.
Microglia are small phagocytic cells that are especially obvious in damaged tissue in the central nervous system (CNS). They are the resident immune cells of the CNS and act as the primary form of active immune defense in the brain.
MHC (Major Histocompatibility Complex) proteins act as a fingerprint of the cell by presenting peptide fragments on the cell surface for immune system recognition. This enables the immune system to distinguish between self and non-self cells, helping to prevent an immune response against the body's own cells.
Cytokines
Microglial cells are the macrophages of the central nervous system (CNS). They act as the primary immune cells in the brain and spinal cord, performing functions like phagocytosis, antigen presentation, and cytokine release to regulate the immune response in the CNS.
The key secretions that control the process of inflammation are cytokines, chemokines, and prostaglandins. These molecules act as signaling agents to recruit immune cells to the site of inflammation, amplify the immune response, and promote the resolution of inflammation.
Dendritic cells are a type of immune cell that play a key role in activating the immune system by capturing, processing, and presenting antigens to other immune cells. They act as messengers between the innate and adaptive immune systems, helping to initiate an immune response against invaders such as pathogens.
Sperm are protected from triggering an immune response because they lack certain proteins on their surface that would typically be recognized as foreign by the immune system. Additionally, the male reproductive system has specialized immune privilege mechanisms to prevent the immune system from attacking sperm cells. This helps to ensure that sperm are not targeted by the immune system and can carry out their function of fertilizing an egg.
Sentinel cells are a type of immune cell that act as the first line of defense against pathogens in the body. They help to detect invaders and initiate an immune response to protect the body from infections. Examples of sentinel cells include dendritic cells and macrophages.
Cytokines, also known as immune factors, are protein produced naturally by the cells and organs of the human immune system. They act on other immune system cells modulating the body's response to disease and infection. Cytokines can also regulate the growth of new blood cells in the bone marrow.Cytokines play a crucial role in the immune system response to all kinds of disease. They interact with organs and cells, alone and in combination with each other. The diverse role that cytokines serve in the immune system make them an ideal target for intervening or bolstering immune responses. Using recombinant DNA technology cytokines can be created in a laboratory. They have many treatment applications including cancer, multiple sclerosis, anaemia, and rheumatoid arthritis.
An antigen is a substance that can invoke an immune response. While an antibody is the immune system's response to an antigen. Antibodies, act by directly neutralizing the antigen and/or bind to the antigen and signaling marcophages to phagocytose the antigen.
Cytokines are special proteins that direct immune and inflammatory responses in the body. They act as messengers between different cells of the immune system, regulating their activities in response to infections and other stimuli. Examples include interleukins, interferons, and tumor necrosis factor.
The exact molecular details of how interferons act is still unclear. They may make surface-exposed antigens of tumors even more capable of stimulating the immune system, which in turn would elicit a greater response from the T-cells of the immune system