actually there are four fates of pyruvate.. usually under aerobic conditions it is converted to acetyl co a. and under anerobic conditions it is converted to lactate. it may also b converted to alanine and oxaloactate by enzymes alt and pyruvate carboxlyse respectively
Pyruvate is changed to ethanol and carbon dioxide through fermentation in the anaerobic pathway in yeast.
The molecule that serves as the common branch point for either the anaerobic or aerobic pathway is pyruvate. Depending on the availability of oxygen, pyruvate can either be converted into acetyl-CoA to enter the aerobic pathway (Krebs cycle or citric acid cycle) or undergo fermentation in the absence of oxygen.
The glycolytic pathway is common to both fermentation and cellular respiration. During the course of the metabolic pathway, glucose is broken down to pyruvate. In the presence of oxygen, the pyruvate molecule becomes involved in the TCA cycle. In the absence of oxygen however, fermentation occures. The process is brought about by an enzyme called alcohol dehydrogenase.
The precursors for gluconeogenesis include lactate, glycerol, and glucogenic amino acids. These substrates can be converted into pyruvate, which then enters the gluconeogenesis pathway to produce glucose.
In the anabolism of glucose, pyruvate is initially converted into phosphoenolpyruvate (PEP) through the enzyme pyruvate carboxylase. PEP is an important intermediate in the gluconeogenesis pathway, which synthesizes glucose from non-carbohydrate precursors.
Glycolysis
Pyruvate is changed to ethanol and carbon dioxide through fermentation in the anaerobic pathway in yeast.
The synthesis of pyruvate occurs in the cytoplasm of the cell during glycolysis. It is the final step in the glycolytic pathway, where glucose is converted to two molecules of pyruvate.
The molecule that serves as the common branch point for either the anaerobic or aerobic pathway is pyruvate. Depending on the availability of oxygen, pyruvate can either be converted into acetyl-CoA to enter the aerobic pathway (Krebs cycle or citric acid cycle) or undergo fermentation in the absence of oxygen.
Glucokinase, phosphofructokinase-1, pyruvate kinase
The EMP pathway, or Embden-Meyerhof-Parnas pathway, is a metabolic pathway involved in glycolysis, which is the process of converting glucose into pyruvate to produce energy for the cell. It is one of the primary pathways for glucose metabolism in cells.
The glycolytic pathway is common to both fermentation and cellular respiration. During the course of the metabolic pathway, glucose is broken down to pyruvate. In the presence of oxygen, the pyruvate molecule becomes involved in the TCA cycle. In the absence of oxygen however, fermentation occures. The process is brought about by an enzyme called alcohol dehydrogenase.
This is the Glycolysis pathway Glycolysis (the breakdown of glucose to pyruvate and lactate, occurs in the cell cytoplasm): Glucose + 2 ATP + 4 ADP + 2 NAD -> 2 Pyruvate + 2 ADP + 4 ATP + 2 NADH + energy. Oxidation of glucose is known as glycolysis. Glucose is oxidized to either lactate or pyruvate. Under aerobic conditions, the dominant product in most tissues is pyruvate and the pathway is known as aerobic glycolysis. When oxygen is depleted, as for instance during prolonged vigorous exercise, the dominant glycolytic product in many tissues is lactate and the process is known as anaerobic glycolysis. "These studies demonstrate that orderly glycolysis in the erythrocyte is regulated by the NAD-to-NADH ratio and also provide a method that makes possible the in vitro study of erythrocyte glycolysis." The conversion of pyruvate to lactate, under anaerobic conditions, provides the cell with a mechanism for the oxidation of NADH (produced during the G3PDH reaction) to NAD which occurs during the LDH catalyzed reaction. This reduction is required since NAD is a necessary substrate for G3PDH, without which glycolysis will cease. Normally, during aerobic glycolysis the electrons of cytoplasmic NADH are transferred to mitochondrial carriers of the oxidative phosphorylation pathway generating a continuous pool of cytoplasmic NAD NADH
Glycolysis is the metabolic pathway that turns glucose into pyruvate and can also produce glucose FROM pyruvate when working in reverse. The major details of this pathway were illuminated largely by three men: Jakub Karol Parnas, Gustav Embden, and Otto Meyerhof. Of these men, only Meyerhof would receive a Nobel Prize.
The victory of the pilgrims that ends with pH is the process of transformation from pyruvate to ethanol during fermentation. This pathway is utilized by organisms like yeast to produce ethanol under anaerobic conditions.
Glycolysis breaks down glucose into pyruvate molecules, producing ATP and NADH in the process.
The precursors for gluconeogenesis include lactate, glycerol, and glucogenic amino acids. These substrates can be converted into pyruvate, which then enters the gluconeogenesis pathway to produce glucose.