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Fructose intolerance is an inherited disorder passed on to children through their parents' genes. Both the mother and father have the gene that causes the condition, but may not have symptoms of fructose intolerance themselves.

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13y ago
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5mo ago

Hereditary fructose intolerance is caused by a genetic mutation in the ALDOB gene. This mutation impairs the enzyme aldolase B, which is necessary for metabolizing fructose. When fructose is not properly metabolized, it can lead to a buildup of toxic byproducts and cause symptoms such as nausea, vomiting, and hypoglycemia.

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Q: What are the causes of hereditary fructose intolerance?
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Can you drink champagne if you have hereditary Fructose intolerance?

Yes you can


What is hereditary fructose intolerance?

Hereditary fructose intolerance is a rare genetic disorder in which the body lacks the enzyme needed to break down fructose, causing a buildup of toxic byproducts. This can lead to symptoms like nausea, vomiting, abdominal pain, and low blood sugar levels after ingesting fructose. Treatment involves following a strict fructose-free diet.


What is the treatment for hereditary fructose intolerance?

Once diagnosed, fructose intolerance can be successfully treated by eliminating fructose from the diet. Patients usually respond within three to four weeks and can make a complete recovery if fructose-containing foods are avoided.


How can hereditary fructose intolerance be prevented?

Hereditary fructose intolerance is a genetic condition, so it cannot be prevented. Management of the condition involves avoiding foods and beverages that contain fructose or sucrose, as well as following a strict diet plan to prevent symptoms. Genetic counseling may be helpful for individuals with a family history of the condition.


How is hereditary fructose intolerance diagnosed?

Hereditary fructose intolerance is usually diagnosed through genetic testing to identify mutations in the aldolase B gene. Additionally, a diagnosis can be confirmed through a fructose challenge test where symptoms are monitored after ingesting fructose. Blood tests measuring specific enzymes levels may also be used to support a diagnosis.


What diseases can cause proximal renal tubular acidosis?

Proximal renal tubular acidosis (type 2) is caused by hereditary diseases, such as Fanconi's syndrome, fructose intolerance, and Lowe's syndrome.


What is the prognosis for a patient with hereditary fructose intolerance?

If the condition is not recognized and the diet is not well controlled, death can occur in infants or young children. With a well-controlled diet, the child can develop normally.


What causes reactive hypoglycemia?

This is still open to debate according to the latest scientific studies in 2013. Some scientists feel that deficiencies in glucagon secretion might lead to this condition, while others thing that the body might be more sensitive than normal to epinephrine, which can cause symptoms of hypoglycemia. Stomach surgery or hereditary fructose intolerance are also felt to be (rare) causes of the condition.


What prevention methods are there to avoid Fanconi's syndrome?

Fanconi's syndrome caused secondarily by the genetic diseases galactosemia, glycogen storage disease, hereditary fructose intolerance, and tyrosinemia is prevented by appropriate dietary restrictions to treat the genetic disease.


What population groups tend to get hereditary fructose intolerance?

One person in about 20,000 is born with this disorder. It is reported more frequently in the United States and Northern European countries than in other parts of the world. It occurs with equal frequency in males and females.


What are the symptoms of hereditary fructose intolerance?

Initial symptoms include vomiting, dehydration, and unexplained fever. Other symptoms include extreme thirst and excessive urination and sweating. There will also be a loss of appetite and a failure to grow. Tremors and seizures caused by low.


What does sugar consumption leads to?

Short Term EffectsHyperactivitySweet taste in mouthPossible negative/positive aftertasteAllergic reactions (for those with hereditary fructose intolerance)Long Term EffectsOral health issues/Tooth decayObesity and weightSugar withdrawal issuesAddiction to sweet foods and drinks