There is gene flow between populations, mating is assortive and natural selection is taking place from the variations offered un by recombination and mutation. Thus, alleles are changing frequency in the population of rats and negating Hardy-Weinberg constraints.
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Some reasons why the rat population may not be in Hardy-Weinberg equilibrium could include factors such as non-random mating (e.g., mating preferences or assortative mating), genetic drift (fluctuations in allele frequencies due to chance events in a small population), gene flow (migration of rats introducing new alleles), mutations (creating new alleles), and natural selection (acting on specific traits or alleles within the population).
In a reversible reaction, the reactants and products become to a dynamic equilibrium after some time. after gaining this equilibrium, when more reactants are added the equilibrium breaks. So according to the Le Chetelier principle, the reaction will proceed until the equilibrium is gained.
Quasi-equilibrium refers to a state in a system where some factors are close to being balanced, allowing for some degree of stability, but not fully achieving a true equilibrium state. It is a concept often used in economics, thermodynamics, and other scientific fields to describe a temporary balance between opposing forces or processes.
The distribution of alleles does not change from one generation to the next
Chemical equilibrium shifts to favor products when the concentration of products is decreased or the concentration of reactants is increased. This can be achieved by removing some of the product or adding more reactant to the system. Le Chatelier's principle states that a system at equilibrium will respond to changes in concentration, pressure, or temperature by shifting in a direction that helps restore equilibrium.
If you remove H½ from the mixture, the equilibrium will shift to the left to compensate for the loss, meaning more H½O will dissociate to reform some of the missing H½. This will increase the concentration of H½O in an attempt to restore equilibrium.