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There are 3 different types of acetylcholinesterase inhibitors - short-acting, medium-duration and irreversible inhibitors, which differ in their interactions with the active site of acetylcholinesterase.=Neostigmine is a medium-duration acetylcholinesterase inhibitor that enhances cholinergic transmission in the central nervous system, autonomic nervous system and at neuromuscular junctions. Acetlycholinesterase inhibitors are an established therapy for Alzheimer's disease and dementia .=
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∙ 15y ago
Neostigmine is a reversible acetylcholinesterase inhibitor, meaning it blocks the activity of acetylcholinesterase enzyme and prevents the breakdown of acetylcholine at the neuromuscular junction. This leads to an increase in acetylcholine levels, enhancing muscle contractions and improving neuromuscular transmission.
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