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Tetracycline is considered a broad-spectrum antibiotic that can treat a wide range of bacterial infections. It is effective against both gram-positive and gram-negative bacteria.
A broad-spectrum antibiotic acts against many different kinds of disease-causing bacteria, including both gram-positive and gram-negative bacteria. A narrow-spectrum antibiotic acts only against specific families of bacteria.
An antibiotic is a natural substance that kills bacteria and can be broad spectrum, effective against a wide range of bacteria, or specific, targeting only certain types of bacteria. Examples of broad-spectrum antibiotics include penicillin and amoxicillin, while examples of specific antibiotics include vancomycin and azithromycin.
Antimicrobial susceptibility tests are used to determine the most effective antibiotic to treat a bacterial infection. It helps guide clinicians in selecting the appropriate antibiotic therapy for patients, taking into account the sensitivity of the bacteria to specific drugs. This test helps prevent the overuse of broad-spectrum antibiotics and reduce the development of antibiotic resistance.
Chloramphenicol is one of the broad spectrum antibiotic used to treat typhoid fever. Resistance occur by way of mutation in ribosomes, By way of decreased permeability of cell wall and production of inactivating enzyme.
An antibiotic should be selectively toxic to the target pathogen while minimizing harm to the host. It should have a broad spectrum of activity against various types of bacteria. The antibiotic should also be stable, have good tissue penetration, and be easy to administer.