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At a basic level, Gluconeogensis is an anabolic process. It involves the creation of a 6 carbon glucose molecule from smaller precursors.

The name gluco (glucose) neo (new) genesis (creation) is quite descriptive of what the pathway does.

Ana-bolic is greek for "upward-throw"

The opposite of gluconeogenesis is glycolysis (glyco for glucose, lysis for breakdown) which is as its name suggests the break down of glucose to form pyruvate and eventually acetyl CoA.

Glycolysis in contrast is considered cata-bolic (greek for downwardthrow)

An easy way I remember the difference is:

catabolism = cutting things up

anabolism = annealing things together

note - When one thinks about where the precursors come from we may consider gluconeogenesis to have a catabolic andanabolic portion. The catabolic process involves the sum of reactions used to generate the precursor molecules (e.g. - breakdown of proteins into amino acids, breakdown of fats into monoacylglycerides and eventually dihydroxyacetone phosphate)

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14y ago

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