There are four different types of hypersensitivities. Type I Hypersensitivities are mostly Allergies and they are exaggerated, misdirected expression of immune responses to an allergen (antigen). The severity of allergies can range from atopy (local allergy such as hay fever or Asthma) or anaphylaxis (a violent and potentially fatal reaction that leads to narrowing of the bronchial airways). Foods, drugs, pollen and bee stings can trigger these reactions and this kind of sensitivity can be transferable to normal people through serum antibody.
An immune response is based on the ability to distinguish molecules that are part of the body ("self") from those that are not ("nonself," or foreign). Such molecules that can elicit an immune response are called antigens.
Antigens incite the immune response by being processed and presented by antigen-presenting cells, such as dendritic cells, to T cells. Once presented, the antigens can activate specific immune responses, leading to the generation of memory cells and effector cells that target the antigen. Antigens that are not processed, reduced, or combined with other proteins may not effectively stimulate the immune system.
HLA1 and HLA2 are located on chromosome 6 in the human genome. They encode proteins that play a key role in the immune system by presenting antigens to T cells for immune responses.
The adaptive immune system was developed in higher vertebrates to combat pathogens and antigens. These can include viruses, bacteria, and anything else that can cause the immune system to launch an immune response.
Antiviral immunity targets viruses by recognizing viral antigens and activating immune responses specific to viral infections. Antibacterial immunity targets bacteria by recognizing bacterial antigens and activating immune responses specific to bacterial infections. The mechanisms of immune cell activation, the types of cells involved, and the specific responses generated differ between antiviral and antibacterial immunity.
Allergies
antigens
An immune response is based on the ability to distinguish molecules that are part of the body ("self") from those that are not ("nonself," or foreign). Such molecules that can elicit an immune response are called antigens.
Fever, Inflammatory myopathies, and vitamin A deficiency.
Regulatory T cells are activated by recognizing specific antigens presented by other immune cells. Once activated, they suppress excessive immune responses to prevent autoimmunity and maintain immune tolerance. They play a crucial role in controlling inflammation and preventing immune reactions against self-tissues.
The five types of antigens are proteins, polysaccharides, lipids, nucleic acids, and glycoproteins. Proteins and polysaccharides are the most common types, often found on the surfaces of pathogens. Lipids and nucleic acids can also elicit immune responses, though they are less common as antigens. Glycoproteins are important in cell recognition and play a role in immune responses as well.
They're abnormal immune responses - by definition, an allergy is an inappropriate response to a foreign substance. After all, it's not known as an 'allergy' when people's immune systems attack harmful pathogens, despite the body mounting somewhat similar immune responses.
Histocompatibility antigens, also known as human leukocyte antigens (HLAs), help the immune system recognize and distinguish between self and non-self cells by serving as markers on the surface of cells. These antigens play a crucial role in immune responses by allowing the immune system to identify and target foreign invaders while avoiding attacking the body's own cells.
Surface antigens on red blood cells (RBCs) play a crucial role in determining blood type and facilitating immune responses. These antigens, such as A, B, and Rh factors, are proteins and carbohydrates that help the immune system recognize self from non-self cells. When blood is transfused, the presence of incompatible antigens can trigger an immune reaction, leading to potentially serious complications. Additionally, these antigens are involved in various physiological processes, including cell signaling and adhesion.
Antigens are important because they trigger responses to pathogens by the immune system. Without them, no prevention against pathogens would take place.
Antigens incite the immune response by being processed and presented by antigen-presenting cells, such as dendritic cells, to T cells. Once presented, the antigens can activate specific immune responses, leading to the generation of memory cells and effector cells that target the antigen. Antigens that are not processed, reduced, or combined with other proteins may not effectively stimulate the immune system.
HLA1 and HLA2 are located on chromosome 6 in the human genome. They encode proteins that play a key role in the immune system by presenting antigens to T cells for immune responses.