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What is a common autosomal trisomy?
Something tells me that trisomy 21 is not really the most common, but it is the common among babies that actually live. Other trisomies common among live births are those of the 13th and 18th chromosome. Trisomy 16 is the most common known disorder of miscarried fetuses. Trisomy is caused by nondisjunction of a pair of chromosomes during meiosis or mitosis. What causes nondisjunction? If we could figure that out, we might be able put trisomies in the past.
How many chromosomes will a zygote with trisomy have?
Meiotic nondisjunction. In meiosis I or II, chromosome pair 21 fail to separate correctly, leaving one gamete with an extra chromosome 21.
Is Down syndrome more severe in mitotic nondisjunction or meiotic nondisjunction?
It's more sever in meiotic nondisjunction, since this is the most common way that trisomy 21 (Down syndrome) arises. mitotic nondisjunction is less sever because it means that some cells will be mosaic, meaning they could be normal while some with have the (2n+1) while other cell will be (2n). So, in mitotic nondisjunction it depend how many cells are carrying the extra 21 chromosome. In end of the day they can't be worse than Down syndrome that rose from meiotic nondisjucntion since it has the highest amount of cells carrying trisomy 21.. I hope this helps
What is a chromosomal disorder that could result from nondisjunction?
Disorders, such as Down's Syndrome, are caused by nondisjunction.
What are nondisjunction genes?
Nondisjunction is the failure of homologous chromosomes or chromatids to segregate during mitosis or meisos with the result that one daughter cell has both of a pair of parental chromosomes or chromatids and the other has none. An example is Trisomy 21, which is also called Down's Syndrome. This person has 3 chromosome #21.Nondisjunction of genes occur during meiosis I when homologous chromosomes fail to separate or during meiosis II when there is unequal distribution of chromosomes. This leads to aneuploidy.
What is a common autosomal trisomy?
Something tells me that trisomy 21 is not really the most common, but it is the common among babies that actually live. Other trisomies common among live births are those of the 13th and 18th chromosome. Trisomy 16 is the most common known disorder of miscarried fetuses. Trisomy is caused by nondisjunction of a pair of chromosomes during meiosis or mitosis. What causes nondisjunction? If we could figure that out, we might be able put trisomies in the past.
How many chromosomes will a zygote with trisomy have?
Meiotic nondisjunction. In meiosis I or II, chromosome pair 21 fail to separate correctly, leaving one gamete with an extra chromosome 21.
Is Down syndrome more severe in mitotic nondisjunction or meiotic nondisjunction?
It's more sever in meiotic nondisjunction, since this is the most common way that trisomy 21 (Down syndrome) arises. mitotic nondisjunction is less sever because it means that some cells will be mosaic, meaning they could be normal while some with have the (2n+1) while other cell will be (2n). So, in mitotic nondisjunction it depend how many cells are carrying the extra 21 chromosome. In end of the day they can't be worse than Down syndrome that rose from meiotic nondisjucntion since it has the highest amount of cells carrying trisomy 21.. I hope this helps
What is a chromosomal disorder that could result from nondisjunction?
Disorders, such as Down's Syndrome, are caused by nondisjunction.
What effects does nondisjunction have on the body if it occurs during mitosis What problems can an individual have if they have nondisjunction in somatic cells?
Nondisjunction during mitosis can lead to aneuploidy, where cells have an abnormal number of chromosomes, which can result in developmental abnormalities or cell death. If an individual has somatic cells with nondisjunction, it can lead to mosaicism, where different cells in the body have different chromosome numbers, potentially causing genetic disorders or health issues.
Does a nondisjunction cause down syndrome?
During meiosis, chromosomes are separated equally. When they are not separated equally - this is known as non-disjunction - the gametes end up with either an extra chromatid or no chromatid. In Down syndrome the offspring carries an extra chromatid in Chromosome 21, aka Trisomy 21.
What is another name for trisomy-21, commonly known as Down syndrome?
Another name for trisomy-21, commonly known as Down syndrome, is trisomy 21.
What are nondisjunction genes?
Nondisjunction is the failure of homologous chromosomes or chromatids to segregate during mitosis or meisos with the result that one daughter cell has both of a pair of parental chromosomes or chromatids and the other has none. An example is Trisomy 21, which is also called Down's Syndrome. This person has 3 chromosome #21.Nondisjunction of genes occur during meiosis I when homologous chromosomes fail to separate or during meiosis II when there is unequal distribution of chromosomes. This leads to aneuploidy.
What kinds of diseases can you get from having too many chromosomes?
Having too many chromosomes, a condition known as aneuploidy, commonly leads to genetic disorders such as Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and Patau syndrome (trisomy 13). These conditions can result in a range of physical and developmental challenges, impacting an individual's health and well-being.
Is non disjunction the only cause of down syndrome?
No.There are three different types of Down syndrome: Standard Trisomy 21, Translocation, and Mosaicism. Standard Trisomy 21 is when the extra chromosome 21 comes from either the egg or sperm cell. Between 90% and 95% of all Down syndrome is Standard Trisomy 21.
What is nondisjunction and why is it harmful?
Nondisjunction is the failure of a homolog to separate during meiosis causing trisomy (an extra chromosome) or monosomy (a missing chromosome), it can be harmful because it is a mutation that can cause many devastating disease, for example nondisjunction of the 21st chromosome causes down syndrome, another example of nondisjunction being harmful, is nondisjunction of the sex chromosomes, causing Turner's or Klinefelter's syndrome two very devastating diseases.
What is the relationship between trisomy 21 and Down syndrome?
Trisomy 21 is down's syndrome, which is an extra copy of chromosome 21
