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One can synthesize this compound starting with benzene or with p-bromoaniline. If you are starting with p-bromoaniline, which is readily available, convert it into the corresponding diazonium salt, and then react it with cuprous chloride. This will give the compound. Make sure the temperatures are low for the reagents or else the phenol will be formed. Extraction in diethyl ether, followed by NaOH wash will give a purer extract. Purification by sublimation will allow the isolaion of the product, BE AWARE OF DIAZONIUM COUPLING REACTIONS AND KEEP THE REAGENTS COLD!

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14y ago
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6mo ago

To synthesize p-chlorobromobenzene, start with bromobenzene and treat it with chlorine in the presence of a Lewis acid catalyst like aluminum chloride. The chlorine will replace one of the hydrogen atoms on the benzene ring, resulting in p-chlorobromobenzene. Purify the product through techniques like fractional distillation or recrystallization.

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10y ago

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Q: How do you synthesize p-chlorobromobenzene?
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