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The gene for hemophilia is found on the 'X' human chromosome. However it is a recessive gene so if a woman (who has two 'XX' chromosomes) has one bad 'X' and one good 'X' she will not have hemophilia but will be a carrier .
If she has female children and their father is not a hemophiliac, then half of her daughters may carry the bad 'X' chromosome but non will manifest the disease.
However, if her children are male then her sons will have an 'X' chromosome inherited from her and a 'Y' chromosome inherited form the father and there is a 50% chance that the 'X' chromosome inherited will be the bad one. If the son inherits the bad 'X' he will be a hemophiliac and if he lives to father any daughters then all these daughters will be hemophilia carriers (because they must inherit his (bad) 'X' chromosome).
It is possible for a woman to manifest hemophilia if the mother is a carrier and the father is a hemophiliac. In this case it is possible for a daughter to inherit the bad 'X' from the father and the mother's bad 'X' giving the daughter two bad 'X' chromosomes.
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SteveYes, males can be carriers for hemophilia. While hemophilia is more common in males, as it is an X-linked genetic disorder, females can also carry the gene and pass it on to their children. Males who inherit the gene will have hemophilia, while females who inherit the gene can be carriers and potentially pass it on to their children.
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What is a carrier for hemophilia?
A carrier for hemophilia is a female who carries the genetic mutation for hemophilia on one of her X chromosomes, but does not exhibit symptoms of the condition herself. Carriers can pass on the gene mutation to their children, resulting in hemophilia in male offspring. Testing can confirm carrier status.
If you know a woman has hemophilia what can you infer about her parents genetype?
If a woman has hemophilia, it means she inherited one affected X chromosome from each of her parents. This suggests that her father is likely a carrier of the hemophilia gene on his X chromosome, and her mother is either a carrier of the gene on one of her X chromosomes or has hemophilia herself.
A woman is a carrier for hemophilia what is the chances for sons with hemophilia if the father does not have hemophilia?
If the mother is a carrier for hemophilia, there is a 50% chance that her sons will inherit the hemophilia gene, but only if the father does not have hemophilia. This is because sons inherit the X chromosome that carries the hemophilia gene from their mother. If the father does not have hemophilia, the son will not inherit a healthy X chromosome from him to compensate for the defective X chromosome from the mother.
What are the offspring of hemophilia?
The offspring of an individual with hemophilia can inherit the condition if they receive the affected gene from their parent. Inheritance follows an X-linked recessive pattern, so males are more likely to be affected while females are typically carriers. Genetic counseling can help assess the risk of offspring inheriting hemophilia.
Could two phenotypically normal parents have a child with Hemophilia A?
XhXh - with hemophilia XhXH- carrier of hemophilia
