Most instruments can play a single note. Exceptions would be things like bagpipes where you have two or more notes played by drones while the melody, a third note, is carried by the chanter; but nearly every other type of instrument can play a single note by bowing, plucking, or striking a single key or string.
Instruments that can only play a single note at a time are things like brass (trumpet, Trombone), woodwinds (oboe, Clarinet, Saxophone), and most other blown instruments (flute).
Electronic instruments like the Theremin and the original Moog synthesizer also can only play a single note at a time. Later synthesizers have multiple sound production channels and can play multiple notes at once. Some instruments are capable of only a single note. Examples would be percussion instruments (gong, cowbell, triangle, bass drum and tomtom) and sound-effect instruments (shotgun in the Huntsman's Waltz, cannons in the 1812 Overture).
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We normally use piano/tune by ear.
The Piccolo is the woodwind that produces the highest sound.
i play a brass instrument and yes one note at a time which can be slurred into another note
nobody is sure what instrument he plays but from the Hanna Montana show Who Could Be The One and in that he plays the bag pipes.
In/On any instrument a quarter note gets one beat.