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Writing about Michelangelo during his lifetime report that for "several months" after finishing the Sistine Chapel he had difficulty reading in any posture but looking up. This was thought to be due to the weeks and months he spent standing on scaffolds and looking up to paint the ceiling. Late in life, he died at age 88, his eyesight had dimmed and was blamed on a lifetime of study. His symptoms would indicate that he developed macular degeneration - not uncommon at that age. Since he finished the Sistine Chapel at age 37 and continued to important architecture work such as St. Peters dome, it is unlikely that the Sistine Chapel work had any major long-term impact on his eyesight.

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