Peyton got shot in season 3 by Jimmy Edwards.
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Keith was shot in season 3 of One Tree Hill by Dan Scott inside Tree Hill High.
Jimmy shot himself in the school and Dan Scott shot Keith Scott in season 3 of One Tree Hill. This all happened in Tree Hill High.
4.09 - Some You Give Away. It's right at the very end, and the song that's playing in the background is: Lessons Learned - Ray LaMontagne Hope that helps! :)
dan Scott shot his brother - Keith - in the school corridor in season 3 at point blank range and in season 4 he then confessed to the police
Keith, Jimmy and Quentin were shot and killed. Keith by Dan, Jimmy committed suicide and Quentin was murdered in a gas station. Peyton was shot in the library during the school shooting but survived it.