No, Nessa isn't Glinda's sister in 'Wicked'. Instead, she's the half sister of Elphaba. They share the same mother, Melena. But they don't share the same father. Their mother has an extramarital affair with the Wizard. Elphaba is the result.
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College-age, as she starts Shiz University at the beginning of our musical.
the sister is the sister of the wicked witch of the west, the wicked witch of the east.
Yes there is.
The Wicked Witch of the East, the sister of the Wicked Witch of the West whom Dorothy melts.
Yes, Elphaba (the wicked witch of the west)'s sister Nessarose (the wicked witch of the east) is in a wheelchair at the beginning of the show. however in Act II, Elphaba enchants her shoes (thus creating the ruby slippers) allowing her to walk.